Keck - Instruments: Differential Scanning Calorimeter

Differential Scanning Calorimeter

The Differential Scanning Calorimeter directly measures the enthalpy of a solution as a function of temperature.

Protein stability and folding
Protein engineering.
Characterization of membranes, lipids, nucleic acids and micellar systems.
Assessment of the effects of structural change and ligand binding on a molecule’s stability.

Instrument Characteristics:

Active cell volume ~ 0.5 ml.

Non-reactive Tantalum 61™ cells for excellent chemical resistance.

Fixed-in-place cells for reproducible ultrasensitive performance with low maintenance.

Operating temperature range of –10ºC to +130ºC.

Peltier element for precise temperature control.

User selectable temperature scan rates (0ºC to 90ºC per hour upscans) and range for application versatility.

DSCfit Software for 2-state analysis of DSC data is available upon request

Location: Cook Hall, 4106

FOM ID: DS CALORIM